Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts
Weichen Zhou, Kalpita R. Karan, Wenjin Gu, Hans‐Ulrich Klein, Gabriel Sturm, Philip L. De Jager, David A. Bennett, Michio Hirano, Martin A. Picard, Ryan E. Mills
The paper quantifies somatic mitochondrial DNA insertions (Numts) in human brain and fibroblasts, showing their accumulation over time and association with lifespan.
PLoS Biology · Aug 22, 2024Peer-reviewedGenomics