Catherine Marneffe

The paper uses a novel viral tool to study early changes in CA3 engram cells' properties after one-trial learning, finding increased excitability and synaptic inputs over time.

This study shows that disrupting presynaptic facilitation at hippocampal mossy fiber synapses reduces CA3 cell co-activity and impairs spatial memory.

The paper analyzes single-cell transcriptomics data from Parkinson's Disease patients and controls to identify cell type-specific molecular responses and pathways involved in neurodegeneration.

The paper identifies molecularly distinct astrocyte subpopulations in the adult mouse brain and shows their spatial distribution has functional implications.

The paper demonstrates that AAV-delivered VHH-B9 reduces amyloid beta levels in an Alzheimer’s disease mouse model.