Author

Brian M. Burkel

University of Wisconsin–MadisonORCID 0000-0002-4170-3808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Suzanne M. PonikiD· 3 shared Alan DaughertyiD· 1 shared B. SahaiD· 1 shared Bahareh BehkamiD· 1 shared Bo Liu· 1 shared Carmel Rebecca Assa· 1 shared David R. InmaniD· 1 shared Elise DeRooiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

Suzanne M. PonikORCID

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3 papers

Recent·Most cited

Biophysicsnpj Breast CancerPeer-reviewedJun 19, 2025

Tumor Stroma Content Regulates Penetration and Efficacy of Tumor-targeting Bacteria

Ying Zhan, B. Saha, Brian M. Burkel…·Bahareh Behkam

This study shows that high collagen content in tumors limits bacterial penetration and reduces the efficacy of Salmonella-based cancer therapy.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 12, 2025

Inhibiting fibronectin assembly in the breast tumor microenvironment increases cell death and improves response to doxorubicin

Metti K. Gari, Hyejin Lee, David R. Inman…·Suzanne M. Ponik

1 citation

mousebulk RNA-seq

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PathologybioRxivPreprintJul 30, 2024

Myeloid-Specific Thrombospondin-1 Deficiency Exacerbates Aortic Rupture via Broad Suppression of Extracellular Matrix Proteins

Ting Zhou, Huan Min Yang, Carmel Rebecca Assa…·Bo Liu

This study shows that myeloid-specific thrombospondin-1 deficiency increases aortic rupture risk by suppressing extracellular matrix proteins and inflammation in aneurysms.

DOI 10.1101/2024.07.30.605216

𝕏 PostBluesky