Douglas V. Laurents

This study characterizes the conformational preferences of C-terminal tails in GroEL, mHsp60, and Cpn60 using spectroscopy, revealing they adopt polyproline II helices rather than being fully disordered.

This study shows that the E134K mutation in SMN disrupts its interaction with GAR1, impairing phase separation and contributing to spinal muscular atrophy.

The paper compares the amyloid-like assembly mechanisms of CPEB prion-like domains from Aplysia and Drosophila, showing divergent pathways leading to a common fold.

This paper investigates the molecular mechanisms of hCPEB3 liquid demixing and amyloidogenesis, identifying key regions and interactions involved in these processes.