Author

Sara S. Félix

Universidade Nova de LisboaORCID 0000-0003-2052-9828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Organism:Drosophila· 2 Assay:structural biology· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Eurico J. CabritaiD· 3 shared Javier OroziD· 2 shared Philip O’TooleiD· 2 shared Aldino ViegasiD· 1 shared Angelo Miguel FigueiredoiD· 1 shared Brígida R. PinhoiD· 1 shared Douglas V. LaurentsiD· 1 shared Douglas Vinson Laurents· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiochemistry

Eurico J. CabritaORCID

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3 papers

Recent·Most cited

BiophysicsInternational Journal of Biological MacromoleculesPeer-reviewedFeb 28, 2026

NMR reveals specific remodelling of protein folding landscapes in ionic liquids

Micael S. Silva, Aldino Viegas, Philip O’Toole…·Eurico J. Cabrita

This paper shows ionic liquids modulate protein folding by stabilizing or destabilizing folded/unfolded states through distinct mechanisms, challenging the conventional view of protein stabilization.

DOI 10.1016/j.ijbiomac.2026.151173

Drosophilaprotein structure

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BiochemistrybioRxivPreprintJan 30, 2025

Pathological mutation in SMN impairs modulation of GAR1 phase separation linking condensate dysfunction to Spinal Muscular Atrophy

Sara S. Félix, Philip O’Toole, Nuno A. S. Oliveira…·Eurico J. Cabrita

This study shows that the E134K mutation in SMN disrupts its interaction with GAR1, impairing phase separation and contributing to spinal muscular atrophy.

2 citations

humanproteomics

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BiochemistryJournal of Biological ChemistryPeer-reviewedDec 1, 2020

Structural transitions in Orb2 prion-like domain relevant for functional aggregation in memory consolidation

Javier Oroz, Sara S. Félix, Eurico J. Cabrita, Douglas Vinson Laurents

This paper studies the structural changes in the Orb2 prion-like domain during memory consolidation using NMR, showing pH-dependent conformational transitions and Zn++-induced aggregation.

DOI 10.1074/jbc.ra120.015211

Drosophilastructural biology

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