NeuroscienceCellPeer-reviewed
Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease
Wei-Ting Chen, Ashley Lu, Katleen Craessaerts…·Bart De Strooper
The paper uses spatial transcriptomics and in situ sequencing to study gene networks in the amyloid-β plaque niche of AD, revealing microglia-astroglia interactions and myelination abnormalities.
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