Karel Kalecký

The paper shows that glutaminolysis and mitochondrial metabolism are conditionally crucial for B cell differentiation and cytokine signaling, revealing metabolic regulation of plasma cell generation and cytokine receptor signaling.

This study identifies B-vitamin deficiencies and genetic variants in one-carbon metabolism pathways associated with cognitive impairment in Alzheimer's and Parkinson's disease.

The paper presents a multi-organ metabolomics atlas in AD mouse models, identifying dysregulated metabolites and microbiome associations linked to oxidative stress and cognitive impairment.

The paper shows FTY720 rescues synaptic plasticity and memory in Alzheimer's model mice by correcting sphingolipid, polyamine, and phospholipid metabolism.

This study evaluates the interlaboratory reproducibility of the MxP(R) Quant 500 metabolomics/lipidomics kit across human and rodent blood samples, showing high consistency and reliability.