Author

Sakshi Krishna

The University of Texas Southwestern Medical CenterORCID 0000-0002-4223-0379Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Dominique LagascaiD· 2 shared Kendra K. FrederickiD· 2 shared Rania DumariehiD· 2 shared Shoyab AnsariiD· 2 shared Yiling XiaoiD· 2 shared Jaka KrageljiD· 1 shared Yang LiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Dominique LagascaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsJournal of the American Chemical SocietyPeer-reviewedMar 27, 2025

Structural context modulates the conformational ensemble of the intrinsically disordered amino terminus of α-synuclein

Rania Dumarieh, Dominique Lagasca, Sakshi Krishna…·Kendra K. Frederick

This study shows that the conformational behavior of α-synuclein's disordered amino terminus varies depending on its structural context and environmental conditions.

6 citations

protein structureexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 9, 2024

Intact cells selectively amplify and structurally remodel amyloid fibrils

Shoyab Ansari, Dominique Lagasca, Rania Dumarieh…·Kendra K. Frederick

This study shows that intact cells selectively amplify and remodel amyloid fibrils of α-synuclein, unlike in vitro or lysate systems.

5 citations

humanproteomics

𝕏 PostBluesky