Author

Shion Orikasa

The University of Texas Health Science Center at HoustonORCID 0000-0002-4226-7358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Noriaki OnoiD· 2 shared Angel Ka Yan Chu· 1 shared Gaurav T. GadhviiD· 1 shared Hiroaki Manabe· 1 shared Javid GhaemmaghamiiD· 1 shared Jialin LiuiD· 1 shared Joshua D. WelchiD· 1 shared Koji Mizuhashi· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Noriaki OnoORCID

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2 papers

Recent·Most cited

BioinformaticsNature GeneticsPeer-reviewedJun 1, 2026

CytoSignal Detects Locations and Dynamics of Ligand-Receptor Signaling at Cellular Resolution from Spatial Transcriptomic Data

Jialin Liu, Hiroaki Manabe, Weizhou Qian…·Joshua D. Welch

CytoSignal detects and quantifies ligand-receptor signaling interactions at cellular resolution from spatial transcriptomic data, enabling spatial gradient analysis and temporal dynamics prediction.

17 citationstop 1%

spatial transcriptomicsstatistical model

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Developmental BiologybioRxivPreprintMay 31, 2023

Growth plate resting zone chondrocytes acquire transient clonal competency upon Hedgehog activation and efficiently transform into trabecular bone osteoblasts

Shion Orikasa, Yuki Matsushita, Michael Fogge…·Noriaki Ono

This study shows that Hedgehog activation in resting zone chondrocytes converts them into osteoblasts through clonal expansion and migration.

1 citation

mouseexperimental assay

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