Author

Yisha Luo

University of ManchesterORCID 0000-0002-4228-7527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Daniel SchindleriD· 2 shared Jef D. BoekeiD· 2 shared Junbiao DaiiD· 2 shared Reem SwidahiD· 2 shared Shuangying JiangiD· 2 shared Yizhi CaiiD· 2 shared Yue SheniD· 2 shared Yun WangiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Daniel SchindlerORCID

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2 papers

Recent·Most cited

Synthetic BiologyCell GenomicsPeer-reviewedNov 1, 2023

Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast

Yue Shen, Feng Gao, Yun Wang…·Yizhi Cai

The paper constructs a synthetic disomic yeast using SCRaMbLE and a newly synthesized chromosome to study aneuploidy phenotypes, finding that both copy number and specific chromosomal regions affect fitness.

35 citations

yeastDNA methylation

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Synthetic BiologyCellPeer-reviewedNov 1, 2023

✦ In-depth digest

Design, Construction, and Functional Characterization of a tRNA Neochromosome in Yeast

Daniel Schindler, Roy S. K. Walker, Shuangying Jiang…·Yizhi Cai

A de novo yeast neochromosome carrying all 275 tRNA genes was built and characterized; it imposes a growth burden, with genome doubling and deletions in haploids possibly reflecting compensation.

81 citationstop 1%

yeastwhole-genome sequencing

𝕏 PostBluesky