Author

Xin Yao

Washington University in St. LouisORCID 0000-0002-4230-5457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Kaiming MaiD· 2 shared Parakkal DeepakiD· 2 shared Chuwen Tian· 1 shared David H. BallardiD· 1 shared Echo Zhu· 1 shared Gwendalyn J. RandolphiD· 1 shared Heather S. RuiziD· 1 shared Jalpa DeviiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Kaiming MaORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 8, 2026

Novel mouse models for perianal fistulizing Crohns disease reveal therapeutic value of interferon-gamma antagonists

Xin Yao, Kaiming Ma, David H. Ballard…·Siyan Cao

This study develops mouse models of perianal fistulizing Crohn's disease and identifies IFN-gamma signaling as a therapeutic target.

DOI 10.64898/2026.06.04.730162

mousebulk RNA-seq

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Systems BiologybioRxivPreprintNov 8, 2024

Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease

Siyan “Stewart” Cao, Khai M. Nguyen, Kaiming Ma…·Parakkal Deepak

The paper uses multi-omics approaches to identify hyperactivated IFNG signaling in PCD, linking it to immune and stromal cell pathogenesis and suggesting IFNG as a therapeutic target.

3 citations

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