Author

Khai M. Nguyen

Washington University in St. LouisORCID 0000-0003-1298-6762Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marco ColonnaiD· 2 shared Antoine DrieuiD· 1 shared Averi Perny· 1 shared Bingying CheniD· 1 shared Bishan BhattaraiiD· 1 shared Bo-Jui ChangiD· 1 shared Claudia Z. HaniD· 1 shared Dagan SegaliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Marco ColonnaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyNeuronPeer-reviewedMar 11, 2026

Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia

Siling Du, Feiya Ou, Antoine Drieu…·Jonathan Kipnis

The paper identifies distinct transcriptional and epigenetic profiles of brain-engrafted monocyte-derived macrophages compared to microglia, showing their origin from peripheral blood and skull bone marrow.

30 citationstop 1%

mousebulk RNA-seq

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Systems BiologybioRxivPreprintNov 8, 2024

Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease

Siyan “Stewart” Cao, Khai M. Nguyen, Kaiming Ma…·Parakkal Deepak

The paper uses multi-omics approaches to identify hyperactivated IFNG signaling in PCD, linking it to immune and stromal cell pathogenesis and suggesting IFNG as a therapeutic target.

3 citations

humanscRNA-seq

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Cancer BiologybioRxivPreprintSep 23, 2024

Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma.

Dagan Segal, Xiaoyu Wang, Hanieh Mazloom-Farsibaf…·Gaudenz M. Danuser

This study identifies Caveolin-1 as a context-dependent regulator of survival signaling in Ewing Sarcoma, revealing a reversible CD99High state with enhanced survival.

DOI 10.1101/2024.09.23.614468

humanbulk RNA-seq

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