Emma Price

This study shows that BORIS, a CTCF paralog, promotes ovarian cancer by altering 3D genome organization and transcriptional programs through chromatin remodeling.

This study uses long-read sequencing to map transposable element variation in human brain tissue, revealing regulatory and epigenetic effects across cell types and ancestries.

This study shows that incomplete silencing of human BORIS in a humanized mouse model leads to increased cancer susceptibility through ectopic gene activation in somatic cells.

This study shows that CTCF binding is influenced by the epigenetic state of the N-terminal nucleosome and its orientation relative to CTCF motifs, affecting chromatin architecture.