Author

Rong Xie

Rush University Medical CenterORCID 0000-0002-8277-7280Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Rong Xie1 paper · Huazhong University of Science and Technology

Biology Disciplines

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Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron B. WaxmaniD· 1 shared Amy WebbiD· 1 shared Ankit A. DesaiiD· 1 shared Anna KirillovaiD· 1 shared Annie M.M. WatsoniD· 1 shared Bing WangiD· 1 shared Caroline Chauvet· 1 shared Chen-Shan Chen WoodcockiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperPhysiology

Aaron B. WaxmanORCID

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2 papers

Recent·Most cited

Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Lloyd D. Harvey, Mona Alotaibi, Yi‐Yin Tai, Ying Tang, Hee‐Jung J. Kim, Neil J. Kelly, Wei Sun, Chen-Shan Chen Woodcock, Sanya Arshad, Miranda K. Culley, Wadih El Khoury, Rong Xie, Yassmin Al Aaraj, Jingsi Zhao, Neha Hafeez, , Stephen Y. Chan

The paper identifies NCOA7's role in lysosomal function and inflammatory sterol metabolism in PAH, showing its deficiency exacerbates disease through oxysterol/bile acid generation.

Science · Jan 23, 2025Peer-reviewedPhysiology

Specific Deletion of Axin1 Leads to Activation of β-Catenin/BMP Signaling Resulting in Fibular Hemimelia Phenotype in Mice

Rong Xie, Dan Yi, Daofu Zeng, Qiang Jie, Qinglin Kang, Zeng Zhang, Zhenlin Zhang, Guozhi Xiao, Lin Chen, Liping Tong, Di Chen

This study shows that Axin1 deletion in mice causes fibular hemimelia by disrupting β-catenin and BMP signaling during limb development.

eLife · Dec 21, 2022Peer-reviewedDevelopmental Biology