Author

Benjamin Aleyakpo

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Drosophila· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adrian M. IsaacsiD· 2 shared Alec J. VincentiD· 2 shared Dongwei XuiD· 2 shared Dunxin SheniD· 2 shared Elli Tsintzas· 2 shared Marie Emilie MaelandiD· 2 shared Sharifah AnoariD· 2 shared Teresa NiccoliiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Adrian M. IsaacsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1 transcription signature

Dunxin Shen, Alec J. Vincent, Evan Udine, Yazead Buhidma, Sharifah Anoar, Elli Tsintzas, Marie Emilie Maeland, Dongwei Xu, Mireia Carcolé, David Osumi-Sutherland, Benjamin Aleyakpo, Alexander J. Hull, Guillermo Martínez-Corrales, Nathaniel S. Woodling, Rosa Rademakers, , Teresa Niccoli

The paper identifies neuronal vulnerability to C9orf72 repeat expansion by analyzing transcriptional states in a Drosophila model, finding that Xbp1 expression correlates with resistance to toxicity.

Cell Reports · Apr 1, 2025Peer-reviewedNeuroscience

A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer's disease models

Dongwei Xu, Alec J. Vincent, Andrés González‐Gutiérrez, Benjamin Aleyakpo, Sharifah Anoar, Ashling Giblin, Magda Luciana Atilano, Mirjam Lisette Adams, Dunxin Shen, Annora Thoeng, Elli Tsintzas, Marie Emilie Maeland, Adrian M. Isaacs, Jimena A. Sierralta, Teresa Niccoli

This study shows that increasing pyruvate import in neurons rescues dementia-like phenotypes in fly models by clearing toxic protein deposits.

PLoS Genetics · Sep 21, 2023Peer-reviewedNeuroscience

Evidence for Involvement of WDPCP Gene in Alcohol Consumption, Lipid Metabolism, and Liver Cirrhosis

Felix O’Farrell, Benjamin Aleyakpo, Rima Mustafa, Xiyun Jiang, Rui Climaco Pinto, Paul Elliott, Ioanna Tzoulaki, Abbas Dehghan, Samantha H. Y. Loh, Jeff W. Barclay, L. Miguel Martins, Raha Pazoki

The paper investigates the role of WDPCP in alcohol consumption, lipid metabolism, and liver cirrhosis using human and model organism studies.

bioRxiv · Apr 11, 2023 · PreprintGenetics