Serge Birman

The paper shows that differences in stress resistance and gut microbiome composition between Drosophila reference lines affect disease modeling outcomes in neurodegenerative conditions.

This study identifies Drospondin, a Drosophila homolog of mammalian Reelin, showing it is essential for nervous system development and function.

This study investigates purine recycling deficiency in Drosophila, showing metabolic and neurobehavioral disturbances similar to Lesch-Nyhan disease in humans.

This study identifies CG31030 as a specific regulator of neuronal V-ATPase in Drosophila, essential for synaptic vesicle acidification and neurotransmitter release.

This study shows that Hedgehog signaling in Drosophila glial cells protects proteostasis and extends lifespan, with potential therapeutic implications for degenerative diseases.