Author

Jon Hazeldine

University of BirminghamORCID 0000-0002-4280-4889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Janet M. LordiD· 2 shared Ahmed Mohamed ElsharkawyiD· 1 shared Alba LlibreiD· 1 shared Amanda Veiga SardeliiD· 1 shared Amritpal DhaliwaliD· 1 shared Caitlin DitchfieldiD· 1 shared Carolyn Anne GreigiD· 1 shared Edward Withnall· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Janet M. LordORCID

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2 papers

Recent·Most cited

Systemic drivers and molecular mechanisms of sarcopenia in aetiology-specific end-stage liver disease

Thomas Nicholson, S. Allen, Jonathan Iain Quinlan, Amritpal Dhaliwal, Michael Macleod, Joshua M. J. Price, Jon Hazeldine, Michael S. Sagmeister, Caitlin Ditchfield, Kirsty C. McGee, Felicity Rhian Williams, Ahmed Mohamed Elsharkawy, Matthew James Armstrong, Carolyn Anne Greig, Janet M. Lord, , Simon Wyn Jones

This study identifies aetiology-specific molecular mechanisms of sarcopenia in end-stage liver disease by analyzing transcriptomic changes and cytokine profiles in muscle and plasma.

Journal of Cachexia Sarcopenia and Muscle · Apr 26, 2026Peer-reviewedMolecular Biology

Physical activity modifies the metabolic profile of CD4+ and CD8+ T cell subtypes at rest and upon activation in older adults

Edward Withnall, Jon Hazeldine, Alba Llibre, Niharika Arora Duggal, Janet M. Lord, Amanda Veiga Sardeli

This study shows that physical activity alters the metabolic profiles of CD4+ and CD8+ T cells in older adults, both at rest and upon activation, potentially improving T cell function.

Aging Cell · May 21, 2025Peer-reviewedImmunology