Author

Silvia Ceschi

University of PaduaORCID 0000-0002-4290-9007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Alfredo J. HernandeziD· 1 shared Anastasia Rastokina· 1 shared André NussenzweigiD· 1 shared Chiara MasnovoiD· 1 shared Elina A. RadchenkoiD· 1 shared Gabriel E. Matos-RodriguesiD· 1 shared Julia A. HiseyiD· 1 shared Nicholas H Mandel· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Alfredo J. HernandezORCID

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1 paper

Recent·Most cited

Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures

Julia A. Hisey, Elina A. Radchenko, Nicholas H Mandel, Ryan J. McGinty, Gabriel E. Matos-Rodrigues, Anastasia Rastokina, Chiara Masnovo, Silvia Ceschi, Alfredo J. Hernandez, André Nussenzweig, Sergei M. Mirkin

This study shows that pathogenic (A2G3)n repeats in CANVAS stall DNA replication by forming alternative DNA structures like triplexes, while nonpathogenic (A4G)n repeats do not.

Nucleic Acids Research · Feb 21, 2024Peer-reviewedGenetics