Author

Elina A. Radchenko

Tufts UniversityORCID 0000-0002-9350-1706Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:yeast· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Sergei M. MirkiniD· 2 shared Alfredo J. HernandeziD· 1 shared Anastasia Rastokina· 1 shared André NussenzweigiD· 1 shared Catie E. Kean· 1 shared Chiara MasnovoiD· 1 shared Gabriel E. Matos-RodriguesiD· 1 shared Grace Materne· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetics

Sergei M. MirkinORCID

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2 papers

Recent·Most cited

Recapitulating the length polymorphism of RS3, a composite microsatellite implicated in human social behavior, via recombination in Saccharomyces cerevisiae

Catie E. Kean, Elina A. Radchenko, Noah M. Lindenbaum, Grace Materne, Sergei M. Mirkin

The paper studies the source of RS3 microsatellite length polymorphism in humans by recapitulating it in yeast and finding it results from recombination.

bioRxiv · Nov 9, 2025 · PreprintGenetics

Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures

Julia A. Hisey, Elina A. Radchenko, Nicholas H Mandel, Ryan J. McGinty, Gabriel E. Matos-Rodrigues, Anastasia Rastokina, Chiara Masnovo, Silvia Ceschi, Alfredo J. Hernandez, André Nussenzweig, Sergei M. Mirkin

This study shows that pathogenic (A2G3)n repeats in CANVAS stall DNA replication by forming alternative DNA structures like triplexes, while nonpathogenic (A4G)n repeats do not.

Nucleic Acids Research · Feb 21, 2024Peer-reviewedGenetics