Author
Gladstone Institutes
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Junichi Saito, Jui M. Dave, Eunate Gallardo‐Vara…·Daniel M. Greif
This study identifies SPHK1 as a key driver of SMC hyperproliferation in elastin deficiency, showing its role in both pathological and physiological arterial remodeling.
Tomohiro Nishino, Sanjeev S. Ranade, Angelo Pelonero…·Deepak Srivastava
The paper uses single-cell multimodal analyses to show how maternal diabetes alters epigenomic and transcriptomic states in cardiac and craniofacial progenitors, leading to developmental defects.
Michael Alexanian, Arun Padmanabhan, Tomohiro Nishino…·Deepak Srivastava
The paper identifies BRD4-dependent immune-fibroblast crosstalk via IL1B in heart failure, showing IL1B inhibition reduces fibroblast activation and improves cardiac function.
Geoffrey A. Smith, Arun Padmanabhan, Bryan Hill-Fung Lau…·John S. Chorba
A genome-wide CRISPR screen identifies CSDE1 as a key regulator of hepatic LDLR mRNA decay in vivo, making it a promising target for heart disease.
Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti…·Deepak Srivastava
The paper identifies a reversible transcriptional switch in cardiac fibroblasts that governs fibroblast plasticity and contributes to chronic heart disease, with MEOX1 as a key regulator.