Author

Xinxin Huang

Shanghai Medical College of Fudan UniversityORCID 0000-0002-4298-4859Unclaimed ORCID profile · follow to get notified of new preprints

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Xinxin Huang2 papers · Zhongda Hospital Southeast University

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

Danhua Xu· 2 shared Hai Gao· 2 shared Jiang XiaoiD· 2 shared Lulu HuiD· 2 shared Mengyao Sheng· 2 shared Chu Xu· 1 shared Chuan HeiD· 1 shared Enzhuo YangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Danhua Xu

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3 papers

Recent·Most cited

Cell surface ribosomal RNA remodeling regulates hematopoietic stem cell trafficking

Nanxi Geng, Min Yang, Xingchao Zeng, Jiang Xiao, Ziqin Yu, Chu Xu, Yu Ye, Danhua Xu, Yuxuan Chen, Mengyao Sheng, Yuanxian Wang, Yuheng Shi, Hai Gao, Lulu Hu, Xinxin Huang

This study identifies cationic agents that regulate hematopoietic stem cell trafficking by remodeling cell surface ribosomal RNA, showing bidirectional control over migration and engraftment.

bioRxiv · Oct 21, 2026 · PreprintCell Biology

Mechanical confinement drives monocyte-to-macrophage differentiation

Wei Liu, Xuezhu Chen, Hao Zhang, Xue Bai, Yong Du, Yu-Xin Ji, Run-Yuan Mao, Ya-Jun Wang, Mengyao Sheng, Hai Gao, Fei Chen, Guangyin Jing, Xinxin Huang, Zhengjun Chen, Yan-Jun Liu

This study shows mechanical confinement drives monocyte-to-macrophage differentiation via a mechanoepigenetic pathway involving KDM6B and H3K27me3 demethylation.

bioRxiv · Apr 1, 2026 · PreprintCell Biology

Small non-coding RNAs encapsulating mammalian cells fuel innate immunity

Jiang Xiao, Xu Chu, Enzhuo Yang, Danhua Xu, Yong Peng, Xue Han, Jingwen Si, Qixin Shao, Zhuo Liu, Qiuxiao Chen, Weizhi He, Shuang He, Yanhui Xu, Chuan He, Xinxin Huang, Lulu Hu

The paper identifies and characterizes surface non-coding RNAs, particularly Y RNAs, on human monocytes and B cells, revealing their role in innate immune activation by regulating IL-6 expression.

bioRxiv · Apr 7, 2025 · PreprintMolecular Biology