Author

Run-Yuan Mao

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Fei CheniD· 2 shared Aixia SongiD· 1 shared Bolin Tao· 1 shared Congling XuiD· 1 shared Guangyin JingiD· 1 shared Hai Gao· 1 shared Hai JiangiD· 1 shared Hai ZhengiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Fei ChenORCID

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Author profile →

2 papers

Recent·Most cited

Mechanical confinement drives monocyte-to-macrophage differentiation

Wei Liu, Xuezhu Chen, Hao Zhang, Xue Bai, Yong Du, Yu-Xin Ji, Run-Yuan Mao, Ya-Jun Wang, Mengyao Sheng, Hai Gao, Fei Chen, Guangyin Jing, Xinxin Huang, Zhengjun Chen, Yan-Jun Liu

This study shows mechanical confinement drives monocyte-to-macrophage differentiation via a mechanoepigenetic pathway involving KDM6B and H3K27me3 demethylation.

bioRxiv · Apr 1, 2026 · PreprintCell Biology

Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition

Pengyu Fan, Xue-Ying Shang, Aixia Song, Shuo Chen, Run-Yuan Mao, Jiwei Chen, Zhenning Wang, Hai Zheng, Bolin Tao, Wei Xu, Wei Jiang, Huijuan Yang, Congling Xu, Peng Zhang, Hai Jiang, Fei Chen

The paper identifies that BET inhibitor efficacy depends on the INTAC complex's auxiliary module, which interacts with the RACK7/ZMYND8-KDM5C complex to remove H3K4 methylation, thereby restoring sensitivity to BET inhibitors through WDR5 degradation.

bioRxiv · Feb 7, 2024 · PreprintMolecular Biology