Author

Kirill V. Rosen

Dalhousie UniversityORCID 0000-0002-4317-9907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1

Frequent Co-Authors

Byong Hoon Yoo· 1 shared Peijia JiangiD· 1 shared Sandhya ChipurupalliiD· 1 shared Xiaoyang LiuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Byong Hoon Yoo

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1 paper

Recent·Most cited

Inactivation of necroptosis-promoting protein MLKL creates a therapeutic vulnerability in colorectal cancer cells.

Peijia Jiang, Sandhya Chipurupalli, Byong Hoon Yoo, Xiaoyang Liu, Kirill V. Rosen

This study shows that inhibiting MLKL in colorectal cancer cells enhances their sensitivity to homoharringtonine, a drug that blocks autophagy, by disrupting VPS37A-dependent autophagy and triggering parthanatos.

Cell Death and Disease · Feb 20, 2025Peer-reviewedCancer Biology