Author

James W. Bruce

University of Wisconsin–MadisonORCID 0000-0002-4323-2966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Amelia M. Hansen· 1 shared Edward L. EvansiD· 1 shared Judd F. HultquistiD· 1 shared Jyothi Krishnaswamy Rajashekar· 1 shared Lacy M. SimonsiD· 1 shared Natalia A. Salazar-QuiroziD· 1 shared Nathan M. ShereriD· 1 shared Paul AhlquistiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Amelia M. Hansen

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1 paper

Recent·Most cited

MicrobiologymBioPeer-reviewedSep 7, 2023

Exploiting rodent cell blocks for intrinsic resistance to HIV-1 gene expression in human T cells

Ryan T. Behrens, Jyothi Krishnaswamy Rajashekar, James W. Bruce…·Nathan M. Sherer

This paper edits human T cells to mimic rodent host factors, creating resistance to HIV-1 and related lentiviruses by disrupting key viral protein interactions.

6 citations

humangenetic perturbation / CRISPR

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