Author

Ping Lü

Peking UniversityORCID 0000-0002-4340-2670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Ao Qi· 1 shared Chan GuiD· 1 shared Fan GuoiD· 1 shared Fan ZhangiD· 1 shared Ge GaoiD· 1 shared Haishan GaoiD· 1 shared Hongtao YuiD· 1 shared Li ChengiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Ao Qi

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 20, 2025

Causality-oriented regulatory inference and rational transcriptomic reprogramming design with CASCADE

Zhi‐Jie Cao, Tianzi Guo, Li Cheng…·Ge Gao

CASCADE is a framework for causal regulatory inference and rational transcriptomic reprogramming design, enabling causal discovery and intervention design for targeted cells.

1 citation

statistical modelmachine learning (classical)

𝕏 PostBluesky

BiophysicsbioRxivPreprintMay 31, 2025

Cryo-EM structure of DNA-unbound human MCM2-7 complex reveals new disease-relevant regulation

Yusong Liu, Mengquan Yang, Ping Lü…·Hongtao Yu

The paper reveals a safety latch mechanism in the DNA-unbound MCM2-7 complex that blocks DNA entry and can be disrupted by mutations, leading to replication defects and DNA damage.

DOI 10.1101/2025.05.31.656953

humancryo-EM

𝕏 PostBluesky