Author

Marshall G. Lougee

University of PennsylvaniaORCID 0000-0002-4351-9908Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

E. James PeterssoniD· 2 shared Benjamin A. GarciaiD· 1 shared Bernard AbakahiD· 1 shared Christopher R. BrueiD· 1 shared David EliezeriD· 1 shared Elizabeth R. RhoadesiD· 1 shared Evan S. K. Yanagawa· 1 shared Grace S. H. Park· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

E. James PeterssonORCID

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2 papers

Recent·Most cited

Determination of α-Synuclein Protein Interactions by μMap Photo-proximity Labeling

Marshall G. Lougee, Grace S. H. Park, Hee Jong Kim, Jiya Fowler, Zongtao Lin, Hossein Fazelinia, Evan S. K. Yanagawa, Vinayak V. Pagar, Tak Ian Chio, Lynn A. Spruce, Virginia M.‐Y. Lee, Benjamin A. Garcia, Melike Lakadamyali, E. James Petersson

This study uses μMap photo-proximity labeling to compare the interactomes of α-synuclein monomers and fibrils in mouse brain lysate to investigate synucleinopathy mechanisms.

Journal of the American Chemical Society · Apr 8, 2026Peer-reviewedBiochemistry

Genetic Code Expansion and Enzymatic Modifications as Accessible Methods for Studying Site-Specific Post-Translational Modifications of Alpha-Synuclein and Tau

Ibrahim G. Saleh, Marie Shimogawa, Jennifer Ramirez, Bernard Abakah, Yarra Venkatesh, Honey Priya James, Minghao Li, Sarah A. Louie, Marshall G. Lougee, Wai‐Kit Chia, Christopher R. Brue, Richard B. Cooley, Ryan A. Mehl, Tobias Baumgart, Robert H. Mach, , E. James Petersson

The paper provides methods for site-specific post-translational modification of alpha-synuclein and tau using genetic code expansion and enzymatic approaches, enabling studies of their structural dynamics and aggregation.

Protein Science · Sep 13, 2025Peer-reviewedBiochemistry