Author

Michael Dewaele

University of LiègeORCID 0000-0002-4380-9374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Carmen Bravo González‐BlasiD· 2 shared Florian RambowiD· 2 shared Gert J. HulselmansiD· 2 shared Jasper WoutersiD· 2 shared Jean‐Christophe MarineiD· 2 shared Stein AertsiD· 2 shared Zeynep Kalender AtakiD· 2 shared Ahmad NajemiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Carmen Bravo González‐BlasORCID

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2 papers

Recent·Most cited

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender Atak, Liesbeth Minnoye, Katina I. Spanier, Maxime De Waegeneer, Carmen Bravo González‐Blas, David Mauduit, Kristofer Davie, Gert J. Hulselmans, Ahmad Najem, Michael Dewaele, Florian Rambow, Samira Makhzami, Valerie Christiaens, Frederik Ceyssens, , Stein Aerts

The paper identifies an intermediate cell state in melanoma through single-cell RNA-seq and ATAC-seq, revealing a gene regulatory network that governs phenotype switching and potential therapeutic targets.

bioRxiv · Aug 8, 2019 · PreprintGenomics

SCENIC: Single-Cell Regulatory Network Inference And Clustering

Sara Aibar, Carmen Bravo González‐Blas, Thomas Moerman, Jasper Wouters, Vân Anh Huynh‐Thu, Hana Imrichová, Zeynep Kalender Atak, Gert Hulselmans, Michael Dewaele, Florian Rambow, Pierre Geurts, J. Aerts, Jean‐Christophe Marine, Joost van den Oord, Stein Aerts

Building gene regulatory networks from scRNA-seq and clustering cells on them identifies stable states robustly to batch effects, applied to mouse and human brain and to melanoma.

Nature Methods · Oct 9, 2017Peer-reviewedBioinformatics