Author

Phurpa Wangchuk

Australian Institute of Tropical Health and MedicineORCID 0000-0002-4381-7382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Darren M. CrayniD· 2 shared Alex C. LoukasiD· 1 shared Catherine MilleriD· 1 shared David T. R. WilsoniD· 1 shared Felix Wambua MuemaiD· 1 shared Gerry TurpiniD· 1 shared Graham Ambridge· 1 shared Joanne F. JamieiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Darren M. CraynORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The Anti-Cancer Effects of Selected Indigenous Medicinal Plants of the Arid Bioregion

Felix Wambua Muema, Suzanne Thompson, Gerry Turpin, Graham Ambridge, Joanne F. Jamie, Darren M. Crayn, Catherine Miller, Lionel Hebbard, Phurpa Wangchuk

This study evaluates the antioxidant, anti-inflammatory, and antiproliferative activities of extracts from seven Australian Indigenous medicinal plants, finding distinct bioactivities with potential relevance to anticancer drug discovery.

bioRxiv · Sep 1, 2026 · PreprintCancer Biology

Plant Molecules Protect Against Inflammatory Bowel Disease by Restoring Gut Microbiota-Immune Homeostasis and Suppressing Pro-inflammatory Markers

Karma Yeshi, Subir Sarker, Md Zohorul Islam, Darren M. Crayn, Stephen G. Pyne, Paul Giacomin, Matthew A. Field, Md. Mizanur Rahaman, David T. R. Wilson, Michael J. Smout, Norelle L. Daly, Alex C. Loukas, Roland Ruscher, Phurpa Wangchuk

This study identifies Garcinia brassii metabolites that reduce inflammation and restore gut microbiota balance in IBD, with garcinia biflavonoid 1 and parvifoliol F showing therapeutic potential.

bioRxiv · Aug 25, 2026 · PreprintImmunology