Christopher C. Lapish

This study uses a piecewise linear recurrent neural network to identify generalizable latent dynamics in neural activity during decision-making in rodents, showing faster rotational dynamics for impulsive choices.

The paper develops a computational model of binge drinking circuitry, showing how interactions between brain regions generate the two-phase drinking pattern.

The paper compares three methods for analyzing spontaneous dopamine signals and finds that z-scoring is unreliable, while manual and prominence methods are more accurate.

This study shows that female mice, but not males, experience reduced corticostriatal theta coherence after repeated binge alcohol drinking.

This study identifies sex differences in neural network reorganization following frontloaded binge alcohol drinking in mice using functional connectivity analysis.

The paper identifies neural signatures of resource-based and resistance-based cognitive control in rats during delay discounting tasks using electrophysiological recordings.

This study assesses aversion-resistant drinking in head-fixed mice and links non-consummatory behaviors to the intensity of this behavior.

The paper examines microcircuit activity in macaque dlPFC using calcium imaging, showing that spontaneous activity is maintained by microcircuit architecture and correlates with cognitive performance.

This study shows that dmPFC encoding changes with delay duration, reflecting deliberative processes at longer delays and impulsive choices at shorter delays.

The paper compares proactive and reactive cognitive control strategies in Wistar and P rats during alcohol-seeking tasks, finding Wistars use proactive control while P rats use reactive control.

The paper identifies specific firing patterns in anterior insular cortex neurons that correlate with compulsion-like alcohol consumption in rats.

This paper develops a computational model of cortico-striatal circuits to study how adaptive and habitual behaviors are controlled, showing that DMS and DLS subregions mediate different learning processes and that impaired executive control enhances inflexible behavior.

This study shows that alcohol preferring P rats continue to drink alcohol mixed with quinine despite aversion, unlike Wistar rats, suggesting a genetic basis for aversion-resistant drinking.

This study shows that rats with a family history of excessive drinking show reduced neural activity in the prefrontal cortex associated with the intention to drink alcohol.

This study examines neural activity in the rat medial prefrontal cortex during an odor span task, identifying distinct activity states associated with different task phases.

This paper models circuit-level mechanisms of ethanol-induced dopamine release from the ventral tegmental area to nucleus accumbens, showing dose-dependent firing changes and the role of synchrony and glutamatergic input.