Developmental BiologyDevelopmentPeer-reviewed
Hypoxia induces a transcriptional early primitive streak signature in pluripotent cells enhancing spontaneous elongation and lineage representation in gastruloids
Natalia López-Anguita, Seher Ipek Gassaloglu, Maximilian Stötzel…·Aydan Bulut-Karslıoğlu
The paper shows hypoxia induces an early primitive streak signature in ES cells, enhancing gastruloid elongation and lineage representation through Hif1-mediated transcriptional changes.
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