Roberto J. Romero

The paper characterizes the urinary microbiota of pregnant women using catheter urine, clean catch urine, and vaginal swabs, finding that Foley catheter urine better captures low-abundance bladder microbes.

This study shows that lipopolysaccharide reduces MNRR1 levels in placental tissues, leading to mitochondrial dysfunction and inflammation via a TLR4-independent pathway.

The paper develops predictive models for preterm birth using maternal blood multi-omics data, finding transcriptomic and proteomic markers can predict gestational age and spontaneous preterm birth with high accuracy.

The paper predicts cellular positions in the Drosophila embryo using scRNA-seq data by benchmarking methods against spatially annotated genes.

The paper investigates ACE2 and TMPRSS2 expression in human placenta across pregnancy stages and finds negligible co-expression, suggesting SARS-CoV-2 is unlikely to infect placenta via canonical entry mediators.

The paper introduces LBBC, a tool to reduce noise in metagenomic cfDNA sequencing, improving detection of urinary tract infection while minimizing false positives.

The paper uses scRNA-seq to analyze placental tissues from term and preterm births, identifying cell type differences and transcriptional signatures associated with labor.

The paper identifies 115 core genes expressed in all eutherian placentas and finds genes associated with placental shape and pre-eclampsia.