Lipopolysaccharide induces placental mitochondrial dysfunction by reducing MNRR1 levels via a TLR4-independent pathway
Neeraja Purandare, Yusef Kunji, Yue Xi, Roberto J. Romero, Nardhy Gomez‐Lopez, Andrew M. Fribley, Lawrence I. Grossman, Siddhesh Aras
This study shows that lipopolysaccharide reduces MNRR1 levels in placental tissues, leading to mitochondrial dysfunction and inflammation via a TLR4-independent pathway.
bioRxiv · Nov 6, 2021 · PreprintMolecular Biology