Ubiquitin-protein ligase Ubr5 cooperates with Hedgehog signalling to promote skeletal tissue homeostasis
David J. Mellis, Katherine Ann Staines, Silvia Peluso, Ioanna Ch. Georgiou, Natalie J. Dorà, Małgorzata Kubiak, Rob vanʼt Hof, Michela Grillo, Colin Farquharson, Elaine Kinsella, Anna Thornburn, Stuart H. Ralston, Donald McGovern Salter, Natalia A. Riobo‐Del Galdo, Robert E. Hill, Mark Ditzel
This study shows UBR5 interacts with the HH pathway to regulate skeletal homeostasis and identifies potential targets for biomedical applications.
PLoS Genetics · Apr 5, 2021Peer-reviewedGenetics