Author

David J. Mellis

Edinburgh Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Andrea CaporaliiD· 1 shared Andrea MartelloiD· 1 shared Angela LauriolaiD· 1 shared Anna Thornburn· 1 shared Colin FarquharsoniD· 1 shared Domenico D’ArcaiD· 1 shared Donald McGovern SalteriD· 1 shared Elaine KinsellaiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Andrea CaporaliORCID

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2 papers

Recent·Most cited

Ubiquitin-protein ligase Ubr5 cooperates with Hedgehog signalling to promote skeletal tissue homeostasis

David J. Mellis, Katherine Ann Staines, Silvia Peluso, Ioanna Ch. Georgiou, Natalie J. Dorà, Małgorzata Kubiak, Rob vanʼt Hof, Michela Grillo, Colin Farquharson, Elaine Kinsella, Anna Thornburn, Stuart H. Ralston, Donald McGovern Salter, Natalia A. Riobo‐Del Galdo, Robert E. Hill, Mark Ditzel

This study shows UBR5 interacts with the HH pathway to regulate skeletal homeostasis and identifies potential targets for biomedical applications.

PLoS Genetics · Apr 5, 2021Peer-reviewedGenetics

Trichoplein controls endothelial cell function by regulating autophagy

Andrea Martello, Angela Lauriola, David J. Mellis, Elisa Parish, John C. Dawson, Lisa H.J. Imrie, Martina Vidmar, Noor Gammoh, Tijana Mitić, Mairi Brittan, Nicholas L. Mills, Neil O. Carragher, Domenico D’Arca, Andrea Caporali

This study shows that Trichoplein regulates endothelial cell function by controlling autophagy, with implications for vascular health and coronary artery disease.

EMBO Reports · Apr 26, 2020Peer-reviewedMolecular Biology