John G. Sled

In 14 BXD mouse strains, those modelling developmental coordination disorder have relatively larger cortex and smaller cerebellar/subcortical volumes; this axis tracks motor coordination but maps to no single QTL.

This study shows that chronic stress worsens microvascular network dysfunction after brain trauma, reducing capillary coordination and vascular reactivity.

The paper identifies stable neuronal representations in cognitively resilient Alzheimer's disease rats during repeated stimulation, suggesting a potential biomarker for cognitive resilience.

This paper introduces a knock-in mouse model of ATR-X syndrome carrying a common patient mutation, showing craniofacial defects, microcephaly, and impaired neurological function.

This study identifies subtle cardiac abnormalities in ASD mouse models, highlighting heterogeneity and potential shared mechanisms with CHD.

This study examines vascular architecture and cerebral blood flow changes after TBI in mice, finding long-term structural and functional alterations.

The paper investigates structural covariance in mouse brain regions, finding that it is explained by distance, transcriptomic similarity, and connectivity, with varying contributions across brain areas.