Author

Yang C. Zeng

Harvard UniversityORCID 0000-0002-4462-9711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Christopher M. WintersingeriD· 2 shared Giorgia IsinelliiD· 2 shared Olivia J. YoungiD· 2 shared William M. ShihiD· 2 shared Amanda R. GravelineiD· 1 shared Andyna VernetiD· 1 shared Catherine J. WuiD· 1 shared David J. MooneyiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Christopher M. WintersingerORCID

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2 papers

Recent·Most cited

Synthetic BiologyNucleic Acids ResearchPeer-reviewedJun 6, 2025

Reusing excess staple oligonucleotides for economical production of DNA origami

Giorgia Isinelli, Christopher M. Wintersinger, Matthew Aquilina…·Yang C. Zeng

This paper demonstrates that reusing excess staple oligonucleotides with replenishment can reduce DNA origami production costs by up to 80%.

7 citations

experimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJun 8, 2022

Fine tuning of CpG spatial distribution with DNA origami for improved therapeutic cancer vaccination

Yang C. Zeng, Olivia J. Young, Christopher M. Wintersinger…·William M. Shih

This study developed a DNA origami-based cancer vaccine that co-delivers antigen and CpG immune adjuvant with an optimal nanospacing for Th1 immune polarization.

14 citations

mouseDNA methylation

𝕏 PostBluesky