Molecular BiologybioRxivPreprint
Enhancing lysosome function via mTOR/TFEB activation reduces lipofuscin-like granules in early Age-related Macular Degeneration
Ana S. Falcão, Mafalda Lopes‐da‐Silva, Pedro Antas…·Miguel C. Seabra
This study shows that activating the mTOR/TFEB pathway reduces lipofuscin-like granules in AMD by improving lysosomal function and POS digestion.
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