Yimiao Qu

The paper identifies two lineage-committed progenitors in the developing brain that generate forebrain/midbrain and hindbrain regions, and demonstrates their distinct chromatin landscapes and differentiation potential.

The paper shows yeast cells use phosphorylation of Whi5 to temporarily remember environmental signals and decide to enter the cell cycle.

The paper challenges a model proposing that protein synthesis increases in pre-Start G1, finding that Whi5 concentration remains constant and Cln3 increase is not due to synthesis.

This study shows that Whi5 in yeast acts as an environmental indicator that coordinates cell growth and division by adjusting cell cycle entry based on environmental conditions.