Elucidating genes sufficient for viral entry into cells through sequential genome-wide CRISPR activation screens
Timothy Chai, Alicia Wong, Qingqing Yin, Isabel von Creytz, Jonathan S. Weissman, Reuben A. Saunders, Joseph B. Prescott, Kyle M. Loh
The paper uses sequential CRISPR activation screens to identify genes sufficient for viral entry into cells, demonstrating effectiveness with Ebola and rabies viruses.
bioRxiv · Mar 6, 2026 · PreprintMicrobiology