Author

Michal Pechar

Czech Academy of SciencesORCID 0000-0002-4507-1801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Robert PolaiD· 2 shared Alexandre DetappeiD· 1 shared Andrea Protti· 1 shared Anna StehlíkováiD· 1 shared Dana Mareková· 1 shared Felix Gremse· 1 shared Florian Trichard· 1 shared G. Mike Makrigiorgos· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Robert PolaORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyFrontiers in ToxicologyPeer-reviewedJun 30, 2026

Modular in vitro evaluation of Buparlisib-polymeric nanomedicines in 2D and 3D models of glioblastoma

Jarmila Havelkova, Yuriy Petrenko, Anna Stehlíková…·Pavla Jendelová

This study evaluates Buparlisib-polymeric nanomedicines in 2D and 3D glioblastoma models, finding that redox-sensitive conjugates show better activity than azide-based ones.

DOI 10.3389/ftox.2026.1783704

humanexperimental assay

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BioengineeringbioRxivPreprintFeb 20, 2018

Targeted Drug Delivery by Radiation-Induced Tumor Vascular Modulation

Sijumon Kunjachan, Shady Kotb, Rajiv Kumar…·Ross Berbeco

This paper demonstrates that combining radiation with gold nanoparticles enhances tumor vascular permeability and improves nanodrug delivery in pancreatic cancer.

DOI 10.1101/268714

humanexperimental assay

𝕏 PostBluesky