Author

Alexander Felix Kiefer

German Center for Infection ResearchORCID 0000-0002-4540-6501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander VoltziD· 1 shared Andreas M. KanyiD· 1 shared Felix DeschneriD· 1 shared Franziska FriesiD· 1 shared Jennifer E. HerrmanniD· 1 shared JUERGEN BARTEL· 1 shared Kai SchließmanniD· 1 shared Nina Walzer· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alexander VoltzORCID

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1 paper

Recent·Most cited

Pathogen-driven reactivation of metabolite prodrugs defines nitroxoline's iron-deprivation antibiotic activity

Felix Deschner, Thorsten Kinsinger, Alexander Felix Kiefer, JUERGEN BARTEL, Alexander Voltz, Kai Schließmann, Nina Walzer, Soeren L Becker, Andreas M. Kany, Franziska Fries, Jennifer E. Herrmann, Rolf Müller

This study identifies nitroxoline's antibacterial mechanism as pathogen-driven reactivation of its metabolites through iron deprivation in uropathogens.

bioRxiv · Jun 11, 2026 · PreprintMicrobiology