Franziska Fries

Pathogen-driven reactivation of metabolite prodrugs defines nitroxoline's iron-deprivation antibiotic activity

This study identifies nitroxoline's antibacterial mechanism as pathogen-driven reactivation of its metabolites through iron deprivation in uropathogens.

Structure Elucidation, Biosynthesis and Biological Evaluation of Neosorangicin A, a Member of the Sorangicin Family

This study isolates and characterizes two new compounds from myxobacteria, elucidates their structures, and evaluates their antimicrobial activity against Gram-positive bacteria.

Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes

This study profiles cystobactamids' off-target effects in eukaryotes, showing safety, superoxide reduction, and SCARB1 inhibition with therapeutic potential.