Kandarp M. Dave

The paper compares sequential centrifugation and density gradient centrifugation for isolating mitochondria-containing large extracellular vesicles.

This study shows that mitochondria-containing large extracellular vesicles (lEVs) improve mitochondrial function in heat-stressed neurons and deliver mitochondria to motor neurons in vivo.

This study compares the therapeutic efficacy of mitochondria-containing extracellular vesicles from mouse and human brain endothelial cells in a mouse stroke model, finding that mouse-derived vesicles are more effective.