Author

Yuta Hikichi

Frederick National Laboratory for Cancer ResearchORCID 0000-0002-6762-3179Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Eric O. FreediD· 3 shared Sherimay D. AblaniD· 2 shared Brian T. LukeiD· 1 shared Caner AkıliD· 1 shared Erin Clark· 1 shared Hana VeleriD· 1 shared Juan R. PerillaiD· 1 shared Juan S. ReyiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Eric O. FreedORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedSep 26, 2025

IFN-inducible Human Phospholipid Scramblase 1 (PLSCR1) ProteinRestricts HIV-1 Infection by Inhibiting Membrane Fusion

Yajie Liu, Pei Li, Yi-Min Zheng…·Shan‐Lu Liu

This study identifies PLSCR1 as a host restriction factor that inhibits HIV-1 and related viruses by blocking membrane fusion during entry, independent of interferon signaling.

4 citations

humanexperimental assay

𝕏 PostBluesky

MicrobiologyScience AdvancesPeer-reviewedSep 12, 2025

Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Strand Transfer Inhibitors

Yuta Hikichi, Ryan C. Burdick, Sean C. Patro…·Eric O. Freed

The paper shows HIV-1 NC mutations accelerate viral DNA integration and reduce INSTI sensitivity, acting with IN mutations to confer resistance.

8 citationstop 3%

humanexperimental assay

𝕏 PostBluesky

MicrobiologyScience AdvancesPeer-reviewedMay 9, 2025

Structural maturation of the matrix lattice is not required for HIV-1 particle infectivity

Long Chen, Yuta Hikichi, Juan S. Rey…·Peijun Zhang

This study shows that an ordered mature MA lattice is not required for HIV-1 infectivity, as a triple mutant lacking this structure remains infectious.

6 citations

humanexperimental assay

𝕏 PostBluesky