Author

Michael J. Holmes

Indiana University IndianapolisORCID 0000-0002-4562-287XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Vishakha DeyiD· 2 shared William J. SullivaniD· 2 shared Emma H. WilsoniD· 1 shared Matheus Silva e BastosiD· 1 shared Ronald C. WekiD· 1 shared Sandeep SrivastavaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

Vishakha DeyORCID

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2 papers

Recent·Most cited

MicrobiologymSpherePeer-reviewedAug 29, 2025

GCN5a is a telomeric lysine acetyltransferase whose loss primes Toxoplasma gondii for latency

Vishakha Dey, Michael J. Holmes, Sandeep Srivastava…·William J. Sullivan

This paper shows that GCN5a loss in Toxoplasma gondii promotes latency by causing telomere dysfunction and altering gene expression during differentiation.

1 citation

ChIP-seqexperimental assay

𝕏 PostBluesky

MicrobiologyJournal of Biological ChemistryPeer-reviewedNov 13, 2024

Cap-independent translation directs stress-induced differentiation of the protozoan parasite Toxoplasma gondii

Vishakha Dey, Michael J. Holmes, Matheus Silva e Bastos…·William J. Sullivan

This study identifies cap-independent translation as a mechanism driving stress-induced differentiation in Toxoplasma gondii by regulating BFD1 protein synthesis.

6 citations

humanexperimental assay

𝕏 PostBluesky