Author

Bei Zhang

Southern Methodist UniversityORCID 0000-0002-4602-5524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adaeze Scholastical Gbufor· 1 shared Anoushka JoglekariD· 1 shared Dmitry KorkiniD· 1 shared Erich David JarvisiD· 1 shared Esha ReddyiD· 1 shared Gloria SheynkmaniD· 1 shared Hagen TilgneriD· 1 shared Isha MondaliD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

Adaeze Scholastical Gbufor

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2 papers

Recent·Most cited

Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Human Glioblastoma Growth by Regulating Mitochondrial Function

Bei Zhang, Ting Cai, Esha Reddy, Yuanna Wu, Isha Mondal, Yinglu Tang, Adaeze Scholastical Gbufor, Jerry Wang, Yawei Shen, Qing Liu, Raymond Sun, Winson S. Ho, Rongze Olivia. Lu, Zhihao Wu

This study identifies msiCAT-tailing of mitochondrial proteins as a mechanism promoting glioblastoma growth by enhancing mitochondrial function and reducing apoptosis.

eLife · Sep 2, 2024Peer-reviewedCancer Biology

Single-cell long-read mRNA isoform regulation is pervasive across mammalian brain regions, cell types, and development

Anoushka Joglekar, Wen Hu, Bei Zhang, Oleksandr Narykov, Mark Diekhans, Jennifer Balacco, Lishomwa C. Ndhlovu, Teresa A. Milner, Olivier D. Fedrigo, Erich David Jarvis, Gloria Sheynkman, Dmitry Korkin, Margaret Elizabeth Ross, Hagen Tilgner

The paper analyzes single-cell long-read mRNA isoform regulation across mouse brain regions, cell types, and development, finding pervasive isoform variability and cell-type specific splicing patterns.

bioRxiv · Apr 2, 2023 · PreprintGenetics