Jyoti Tripathi

This paper identifies SARS-CoV-2 PLpro as a driver of epithelial stress and tissue damage across species by activating metabolic and inflammatory pathways in Drosophila and mammalian models.

This study shows that RasG12V-induced epithelial senescence in Drosophila triggers host metabolic syndrome through cytokine signaling, linking oncogene-induced senescence to metabolic disorders.