Martin Lacher

This study shows that overactivated NF-κB disrupts lung development in CDH and that dexamethasone or curcumenol can rescue lung hypoplasia by normalizing NF-κB signaling.

Amniotic fluid stem cell extracellular vesicles improve fetal lung development in CDH by modulating macrophage inflammation and restoring normal gene expression.

The paper uses proteomic profiling to identify inflammatory processes as a key factor in the pathogenesis of lung hypoplasia in congenital diaphragmatic hernia.