Author

Ian John McGough

Babraham InstituteORCID 0000-0002-4622-5358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Organism:mouse· 1

Frequent Co-Authors

Ana-Miruna Androniciuc· 1 shared Asif NakhudaiD· 1 shared Aude Maugarny-CalèsiD· 1 shared Aurora Xinshu Xu· 1 shared Bernard D. KeavneyiD· 1 shared Cyrille Alexandre· 1 shared E. Yvonne JonesiD· 1 shared Gennadiy TeniniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Ana-Miruna Androniciuc

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2 papers

Recent·Most cited

GPC6 Lipid Shielding Sustains WNT5A Gradients to Prevent a RASopathy-like Developmental State

Yeonjoo Kim, Yuguang Zhao, Aurora Xinshu Xu, Asif Nakhuda, Ana-Miruna Androniciuc, Gennadiy Tenin, Bernard D. Keavney, E. Yvonne Jones, Ian John McGough

The paper shows that GPC6 shields WNT5A lipid to maintain gradients, and its disruption causes a RASopathy-like developmental state by promoting premature signaling.

bioRxiv · Sep 22, 2026 · PreprintDevelopmental Biology

Frizzled-dependent Planar Cell Polarity without Wnt Ligands

Joyce J.S. Yu, Aude Maugarny-Calès, Stéphane Pelletier, Cyrille Alexandre, Yohanns Bellaı̈che, Jean‐Paul Vincent, Ian John McGough

The paper shows that Wnt ligands are not essential for Planar Cell Polarity (PCP) in Drosophila wings, as PCP remains normal in the absence of Wnt signaling.

Developmental Cell · Sep 1, 2020Peer-reviewedDevelopmental Biology