Jean‐Paul Vincent

This study identifies three distinct mechanisms by which Xrp1 is induced in response to different stresses in Drosophila, highlighting its role in the Integrated Stress Response.

This paper introduces FlyMOE, a chemical-genetic platform for targeted glycoproteome analysis in Drosophila, using mass spectrometry to study glycosylation in vivo.

This study shows that membrane lipid composition and endocytosis regulate Wingless release from secreting cells by modulating its dissociation from Wntless.

The paper identifies a genetic circuit in Drosophila that enhances BMP signaling at the distal end of the gradient, enabling insect wing development.

The paper shows that growth deceleration during development is linked to hypoxia, with HIF-1 regulating TOR signaling to prevent oxygen demand from exceeding supply.

The paper investigates how signalling networks and tissue flows interact during vein refinement in Drosophila pupal wings, showing that cell fate adjustments, not large-scale flows, drive precise patterning.

The paper shows that ecdysone receptor activity promotes or suppresses proliferation depending on ligand levels, with distinct transcriptional responses to different ecdysone doses.

The paper shows that Wnt ligands are not essential for Planar Cell Polarity (PCP) in Drosophila wings, as PCP remains normal in the absence of Wnt signaling.

The paper describes CRISPR/Cas9-based tools for creating genetic modifications in Drosophila and highlights challenges and solutions in genome engineering.

The paper shows that EGFR signaling coordinates patterning with cell survival in Drosophila epidermis by regulating pro-apoptotic gene expression based on ligand availability.